Schematic representation of the PluriPotent precursor strategy

A schematic representation of the post-synthetical production of a vast number of 2'-modified oligonucleotides from a single precursor oligonucleotide. The modifier (HNu) can be any of a number of primary aliphatic amines, amino alcohols, hydroxide, or ammonia. The final products can have a user-desired functionality found within the Nu moiety

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