Sequencing at Fidelity Systems

Towards Direct Sequencing Animal and Human DNA

     Although direct sequencing of animal and human DNA is much more difficult than sequencing microbial genome because of very low relative content of specific DNA templates, we have successfully performed direct sequencing off gigabase DNA on several occasions.

     Direct sequencing off gigabase DNA: fish genome (1.5 Gb).


Genomic DNA
(Fringilla coelebs L.)


Plasmids with
the cloned

     Direct sequencing off avian genomic DNA: SNPs in FCP repeats of chaffinch.



     Direct sequencing of gigabase DNA; human chromosomal template: identity of 3 genomic samples and alignment with GenBank entry.


Covered by U.S. Patents 5,427,928, 5,656,463, 5,902,879, 6,548,251. Patents pending. Fidelase, ThermoFidelase, D-Strap and Fimer are trademarks of Fidelity Systems.
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