Towards Direct Sequencing Animal and Human DNA
Although direct sequencing of animal and human DNA is much more difficult than sequencing microbial genome because of very low relative content of specific DNA templates, we have successfully performed direct sequencing off gigabase DNA on several occasions. Direct sequencing off gigabase DNA: fish genome (1.5 Gb).
Direct sequencing of gigabase DNA; human chromosomal template: identity of 3 genomic samples and alignment with GenBank entry.
Covered by U.S. Patents 5,427,928, 5,656,463, 5,902,879, 6,548,251. Patents pending. Fidelase, ThermoFidelase, D-Strap and Fimer are trademarks of Fidelity Systems. |